Burger King (100 points): Win the BK Invitational fight.

Dodge (100 points): Win the Dodge sponsored fight.

EA Sports (150 points): Win any EA Sports sponsored fight.
ESPN FNF (150 points): Win any ESPN Friday Night Fight event.
ESPN PPV (150 points): Win any ESPN Pay-Per-View fight event.
ESPN WNF (150 points): Win any ESPN Wednesday Night Fight event.
Everlast (100 points): Win the Everlast sponsored fight.

Under Armour (100 points): Win the Under Armour sponsored fight.

All venues  -  Enter "NEWVIEW" as a first name in Create Champ mode to unlock all venues.

Bonus venues  -  Win a match at one of the corresponding venues in Career mode to unlock it:

Madison Square Garden
The Staples Center

Box as Ko Rey Mo  -  Defeat Ko Rey Mo in the light heavy division in Career mode to unlock him.

Burger King trainer  -  Win the Burger King event in Career mode. Then at the trainer selection screen, press Down until the Burger King appears as a choice. He gives you Heart when you fight.

Boxing styles  -  Win matches in ESPN Classic Fights mode or Career mode to unlock various new styles, at random:

Hard Straights
Hook Master

Judge Jab

Lethal Uppercuts

Philly Shell

Sinister Cross
Slickster
Smooth

Textbook

Uptight

Easy wins in Career mode  -  Go to the options menu and set "Illegal Blows" to "Off". Then, go to the fight store and buy the illegal head punch called "Elbow Shot". During a fight, use the Elbow Shot to counter attack each time your opponent throws a punch. Note: Make sure you use the Elbow Shot as a counter attack so that you can connect cleanly and powerfully on you opponent's head. You will see that the Elbow Shot inflicts a lot of damage to your opponent, and will KO him in a short period of time, or TKO because you inflicted so much damage to his eyes.

Remain undefeated  -  During any fight in Career mode, if you get knocked down and you think you are not going to make it, turn your Xbox 360 off before the bell rings. When the game is resumed, you can start the match again without a loss.