Note: This game is also known as - Biohazard 5

VZ61 machine gun in Public Assembly - After the gate has broken open, you can enter the market. Go all the way down the street until you see big red doors and gas cans next to them. Turn right just before the gas cans. There will be a brief case you can open with a VZ61 machine gun in it. If you look closely, the gun resembles the "Scorpion" sub machine gun in Call Of Duty 4. This gun makes the level much easier.

Staying together in Shanty Town - Go up to the building that has two frag grenades. You can go off of the edge and bounce them off of the "KENNYS" sign. If done correctly, this will blow off the lock, eliminating the need for Chris and Sheva to be separated.

Lure away move - Press L3 + R3 to do the "lure away" move, where Chris will say "Come on, come on!" or Sheva will whistle. This lures regular enemies towards you, just in case your partner is low on health, trying to pull something off, cranking something, etc.

Trophies - Successfully complete one of the following tasks to get a trophy:

Completed Chapter 1 - 1 (Bronze): Complete Chapter 1 - 1 on any difficulty setting.
Completed Chapter 1 - 2 (Bronze): Complete Chapter 1 - 2 on any difficulty setting.
Completed Chapter 2 - 1 (Bronze): Complete Chapter 2 - 1 on any difficulty setting.
Completed Chapter 2 - 2 (Bronze): Complete Chapter 2 - 2 on any difficulty setting.
Completed Chapter 2 - 3 (Bronze): Complete Chapter 2 - 3 on any difficulty setting.
Completed Chapter 3 - 1 (Bronze): Complete Chapter 3 - 1 on any difficulty setting.
Completed Chapter 3 - 2 (Bronze): Complete Chapter 3 - 2 on any difficulty setting.
Completed Chapter 3 - 3 (Bronze): Complete Chapter 3 - 3 on any difficulty setting.
Completed Chapter 4 - 1 (Bronze): Complete Chapter 4 - 1 on any difficulty setting.
Completed Chapter 4 - 2 (Bronze): Complete Chapter 4 - 2 on any difficulty setting.
Completed Chapter 5 - 1 (Bronze): Complete Chapter 5 - 1 on any difficulty setting.
Completed Chapter 5 - 2 (Bronze): Complete Chapter 5 - 2 on any difficulty setting.
Completed Chapter 5 - 3 (Bronze): Complete Chapter 5 - 3 on any difficulty setting.
Completed Chapter 6 - 1 (Bronze): Complete Chapter 6 - 1 on any difficulty setting.
Completed Chapter 6 - 2 (Bronze): Complete Chapter 6 - 2 on any difficulty setting.
Completed Chapter 6 - 3 (Bronze): Complete Chapter 6 - 3 on any difficulty setting.
Recruit (Bronze): Complete all chapters on Amateur.
Soldier (Bronze): Complete all chapters on Normal.
Egg Hunt (Bronze): Find all 4 types of eggs.
A Friend in Need (Bronze): Save partner 10 times when HELP is displayed.
Lifeguard (Bronze): Save partner 10 times when DYING is displayed.
Exploding Heads (Bronze): Pull off 20 headshots.
A Cut Above (Bronze): Defeat 5 enemies with the Knife.
Cattle Prod (Bronze): Defeat 30 enemies with the Stun rod.
Crowd Control (Bronze): Defeat 30 enemies with the Gatling gun.
Bull's-eye (Bronze): Defeat 30 enemies with the Longbow.
Get Physical (Bronze): Defeat 20 enemies with physical attacks.
The Works (Bronze): Chain the maximum number of combos together in one go.
Fireworks (Bronze): Shoot an enemy Molotov cocktail, dynamite stick, or hand grenade.
Meat Shower (Bronze): Defeat 3 Majini with one grenade or proximity bomb.
Go into the Light (Bronze): Defeat 2 enemies with one flash grenade.
Ride the Lightning (Bronze): Defeat a Majini using the electric current from a transformer.
Stop, Drop, & Roll (Bronze): Defeat 3 Majini at once by setting oil canisters on fire.
Baptism by Fire (Bronze): Defeat 3 Majini at once with a drum or gas tank explosion.
Masters of Removing (Bronze): Work together to save someone special.
Egg on Your Face (Bronze): Defeat a Majini with a rotten egg.
Heart Stopper (Bronze): Defeat a certain enemy by stabbing it in the heart.
Veteran (Silver): Complete all chapters on Veteran.
All Dressed Up (Silver): Purchase all available alternative costumes in Bonus Features.
Stockpile (Silver): Obtain all available weapons.
Take It to the Max (Silver): Completely upgrade all weapons.
They Belong in a Museum (Silver): Obtain all treasures in the game.
Badge of Honor (Silver): Find all the BSAA emblems.
They're ACTION Figures! (Silver): Collect all the figurines.
Lead Aspirin (Silver): Defeat a Majini with a headshot while it's jumping.
Be the Knife (Silver): Deflect a bow gun arrow with your knife.
Drive By (Silver): Stop an armored truck by taking out the driver.
Who Do You Trust? (Silver): Build up a certain level of trust with your partner.

Additionally, there are three secret trophies:

Bad Blood (Bronze): During the first fight with Wesker, damage him a set number of times.
War Hero (Bronze): Complete all chapters on Professional.
Resident Evil 5 Platinum Trophy (Platinum): Congratulations! You've overcome all your fears in Resident Evil 5.